The relation between humidex and comfort is subjective, and varies widely between individuals. Environment Canada provides the following guide as a measure of discomfort according to humidex:
| Humidex Range | Degree of Comfort |
| 20-29°C | most people are comfortable |
| 30-39°C | people experience some discomfort. |
| 40-45°C | people are uncomfortable; avoid exertion |
| above 45°C | dangerous conditions exist and many types of labour must be restricted. |
| above 54°C | heat stroke imminent |
* The American Society of Heating, Refrigerating, and Air Conditioning Engineers (ASHRAE) Standard "Thermal environmental conditions for human occupancy" recommends temperature ranges of 20°C to 26°C at 50% relative humidity as comfortable for sedentary work. An air temperature of 26°C at 50% relative humidity corresponds to a humidex of 29°C.